个人简介：

潘明珠，女，博士，讲师，金沙js800000专职教师。

研究方向：

水产动物营养与免疫、水产动物细胞生物学

发表论文：

（1）Pan, M., Liu, J., Huang, D., Guo, Y., Luo, K., Yang, M., ... & Mai, K. (2021). FoxO3 Modulates LPS-Activated Hepatic Inflammation in Turbot (Scophthalmus maximus L.). Frontiers in immunology, 12.

（2）Pan, M.*, Liu, D.*, Liu, J., Li, X., Huang, D., Luo, K., ... & Mai, K. (2022). Biotin alleviates hepatic and intestinal inflammation and apoptosis induced by high dietary carbohydrate in juvenile turbot (Scophthalmus maximus L.). Fish & Shellfish Immunology, 130, 560-571. (*共同一作)

（3）Pan, M., Zhang, Y., Deng, K., Liu, G., Gu, Z., Liu, J., ... & Mai, K. (2019). Forkhead box O1 in turbot Scophthalmus maximus: Molecular characterization, gene structure, tissue distribution and the role in glucose metabolism. Gene, 708, 49-56.

（4） Gu, Z.*, Pan, M.*, Liu, J., Yang, M., Zhang, W., & Mai, K. (2022). Molecular cloning of AKT1 and AKT2 and their divergent responses to insulin and glucose at transcriptional level in the liver of Japanese flounder Paralichthys olivaceus. Aquaculture Reports, 23, 101066. (*共同一作)

（5） Deng, K., Pan, M., ... & Mai, K. (2018). Chronic stress of high dietary

carbohydrate level causes inflammation and influences glucose transport through SOCS3 in Japanese flounder Paralichthys olivaceus. Scientific reports, 8(1), 1-13.

（6） Liu, J., Pan, M., Huang, D., Guo, Y., Yang, M., Zhang, W., & Mai, K. (2020). Myostatin-1 inhibits cell proliferation by inhibiting the mTOR signal pathway and MRFs, and activating the ubiquitin-proteasomal system in skeletal muscle cells of Japanese flounder Paralichthys olivaceus. Cells, 9(11), 2376.

（7） Liu, J., Pan, M., ... & Mai, K. (2022). High glucose induces apoptosis, glycogen accumulation and suppresses protein synthesis in muscle cells of olive flounder Paralichthys olivaceus. British Journal of Nutrition, 127(11), 1601-1612.

（8） Yang, M., Pan, M., Huang, D., Liu, J., Guo, Y., Liu, Y., & Zhang, W. (2023). Glucagon Promotes Gluconeogenesis through the GCGR/PKA/CREB/PGC-1α Pathway in Hepatocytes of the Japanese Flounder Paralichthys olivaceus. Cells, 12(7), 1098.

（9） Liu, J., Pan, M., Liu, Y., Huang, D., Luo, K., Wu, Z., ... & Mai, K. (2022). Taurine alleviates endoplasmic reticulum stress, inflammatory cytokine expression and mitochondrial oxidative stress induced by high glucose in the muscle cells of olive flounder (Paralichthys olivaceus). Fish & Shellfish Immunology, 123, 358- 368.

（10） Liu, J., Deng, K., Pan, M., Liu, G., Wu, J., Yang, M., ... & Mai, K. (2020). Dietary carbohydrates influence muscle texture of olive flounder Paralichthys olivaceus through impacting mitochondria function and metabolism of glycogen and protein. Scientific reports, 10(1), 1-20.

（11） Yang, M., Deng, K., Pan, M., ... & Mai, K. (2019). Glucose and lipid metabolic adaptations during postprandial starvation of Japanese flounder Paralichthys olivaceus previously fed different levels of dietary carbohydrates. Aquaculture, 501, 416-429.

（12） Yang, M., Deng, K., Pan, M., … & Mai, K. (2020). Molecular adaptations of glucose and lipid metabolism to different levels of dietary carbohydrates in juvenile Japanese flounder Paralichthys olivaceus. Aquaculture Nutrition, 26(2), 516-527.

（13） Huang, D., Guo, Y., Li, X., Pan, M., … & Mai, K. (2021). Vitamin D3/VDR inhibits inflammation through NF-κB pathway accompanied by resisting apoptosis and inducing autophagy in abalone Haliotis discus hannai. Cell Biology and Toxicology, 1-22.

（14） Liu, D., Zhang, Y., Pan, M., Yang, M., Li, X., Fu, Y., ... & Mai, K. (2021).

Interactive effects of dietary biotin and carbohydrate on growth performance and glucose metabolism in juvenile turbot Scophthalmus maximus L. Aquaculture, 540, 736752.

（15） Liu, G., Wang, L., Yu, H., Pan, M., Yang, M., Zhang, W., & Mai, K. (2021). Effects of dietary protein levels on growth performance, digestibility, anti‐ oxidative responses and expressions of growth-related genes in triploid rainbow trout Oncorhynchus mykiss farmed in seawater. Aquaculture Nutrition, 27(4), 998-1008.

（16） Guo, Y., Huang, D., Pan, M., Yang, M., Luo, K., Liu, J., ... & Mai, K. (2021). High dietary lipid level decreases the immunity and disease resistance of abalone Haliotis discus hannai and affects the perilipin‐2/TLR4, JNK and Keap1/Nrf2 pathways. Aquaculture Nutrition, 27(6), 2042-2055.

（17） Liu, Y., Yu, H., Guo, Y., Huang, D., Liu, J., Pan, M., ... & Mai, K. (2021). Arginine Regulates TOR Signaling Pathway through SLC38A9 in Abalone Haliotis discus hannai. Cells, 10(10), 2552.

（18） Liu, D., Deng, K., Sampath, W. W. H. A., Gu, Z., Pan, M., Zhang, Y., ... & Mai, K. (2019). Responses of glucosensing system to glucose in Japanese flounder Paralichthys olivaceus fed diets with different carbohydrate content. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 232, 72-78.

（19） Luo, K., Li, X., Wang, L., Rao, W., Wu, Y., Liu, Y., Pan, M., Huang, D., Zhang, W., Mai, K., 2021. Ascorbic Acid Regulates the Immunity, Anti-Oxidation and Apoptosis in Abalone Haliotis discus hannai Ino. Antioxidants. 10, 1449.

（20） Wang, L., Guo, Y., Pan, M., Li, X., Huang, D., Liu, Y., ... & Mai, K. (2021). Functions of forkhead box O on glucose metabolism in abalone Haliotis discus hannai and its responses to high levels of dietary lipid. Genes, 12(2), 297.

（21） Wu, Z., Yu, X., Guo, J., Fu, Y., Guo, Y., Pan, M., ... & Mai, K. (2022). Replacement of dietary fish meal with Clostridium autoethanogenum protein on growth performance, digestion, mTOR pathways and muscle quality of abalone Haliotis discus hannai. Aquaculture, 553, 738070.

（22） Wu, Z., Yu, X., Guo, J., Fu, Y., Guo, Y., Pan, M., ... & Mai, K. (2022). Effects of replacing fish meal with corn gluten meal on growth performance, intestinal microbiota, mTOR pathway and immune response of abalone Haliotis discus hannai. Aquaculture Reports, 23, 101007.

（23） Zhang, Y., Wei, Z., Liu, G., Deng, K., Yang, M., Pan, M., ... & Mai, K. (2019). Synergistic effects of dietary carbohydrate and taurine on growth performance, digestive enzyme activities and glucose metabolism in juvenile turbot Scophthalmus maximus L. Aquaculture, 499, 32-41.

（24） Zhang, Y., Wei, Z., Yang, M., Liu, D., Pan, M., Wu, C., ... & Mai, K. (2021). Dietary taurine modulates hepatic oxidative status, ER stress and inflammation in juvenile turbot (Scophthalmus maximus L.) fed high carbohydrate diets. Fish & Shellfish Immunology, 109, 1-11.

（25） Chen, P., Huang, D., Li, X., Pan, M., Wu, Z., Rao, W., ... & Zhang, W. (2023). Interaction between dietary lipid and bile acids on the growth performance and lipid metabolism in abalone Haliotis discus hannai Ino. Aquaculture Reports, 30, 101560.

（26） Fall, F. N., Ma, S., Sahandi, J., Chibuikem, C. K., Pan, M., Tabuariki, B. B., ... & Zhang, W. (2023). Interactions between dietary protein level and water temperature on the growth performance, innate immunity and disease resistance of juvenile abalone Haliotis discus hannai Ino. Aquaculture Reports, 30, 101559.

授权专利：

（1） 张文兵, 潘明珠, 刘家欢, 李昕昕, 杨梦曦, 黄冬, 郭衍林, 罗凯, 刘玥, 麦康森. 一种大菱鲆肝实质细胞系的建立方法及细胞系. 专利号：ZL 202110645948.2, 2022-12-06.

（2） 张文兵, 潘明珠, 刘家欢, 马硕利, 刘玥, 黄冬, 郭衍林, 麦康森. 一种皱纹盘鲍鳃细胞的快速原代培养方法及应用. 专利号：ZL 202010728586.9, 2022-10-11.

（3） 张文兵, 刘家欢, 潘明珠, 马硕利, 黄冬, 刘玥, 郭衍林, 麦康森. 鲍细胞培养基及鲍细胞培养方法. 专利号：ZL 202010728588.8, 2022-06-07.

（4） 张文兵, 刘玥, 刘家欢, 潘明珠, 黄冬. 皱纹盘鲍肝胰腺细胞的分离和原代培养方法. 专利号：ZL 202011531779.1, 2022-09-13.